Alphonse-Marie is a primarily masculine compound given name. Bearers of the name include:

Alphonse-Marie Bérenger (1785–1866), French lawyer and politician Alphonse-Marie Eppinger (1814–1867), born Elisabeth Eppinger, French Catholic nun and founder of the Sisters of the Divine Redeemer Alphonse-Marie Kadege, Burundian politician and former Vice-President of Burundi Alphonse-Marie Parent (1906–1970), Canadian priest, educator and academic administrator

See also Alphonse Marie Fons Rademakers (1920–2007), Dutch actor, director, producer and screenwriter Mary Barr Mackinlay (1910–1974), also known as Sister Alphonse Marie, Australian Dominican sister Marie-Alphonse, another given name