Marie-Léonie is a feminine compound given name. Bearers of the name include:
Marie-Léonie Graftieaux, birth name of Marcelle Dormoy (1895–1976), French couture fashion designer and model Marie-Léonie Léon (1838–1906), French courtesan Marie-Léonie Paradis (1840–1912), French-Canadian Catholic saint and sister
See also Marie Léonie Jahn, birth name of Léonie Yahne (1867–1950), French comedic actress Marie Léonie Vanhoutte (1888–1967), French secret agent during World War I Marie Léonie Tietjens, a major character in Last Post, a Ford Madox Ford novel