Marie-Charlotte is a feminine compound given name. Persons bearing the name include:

Marie-Charlotte de Balzac d'Entragues (c. 1588–1664), French noblewoman and mistress to King Henry IV of France Marie-Charlotte Garin (born 1995), French politician Marie-Charlotte Léger (born 1996), French footballer Marie-Charlotte Pascal (1749–1821), wife of French banker Claude-Nicolas Perier, many of whose children attained influential positions

See also Marie Charlotte Blanc (1833–1881), German socialite and businesswoman, operator of the Monte Carlo Casino Marie Charlotte of East Frisia (1689–1761), by marriage Countess of Kriechingen, as well as Lady of Püttlingen Marie Charlotte Fayanga (1946–2021), Central African diplomat and politician Marie Charlotte Hippolyte de Saujon (1725–1800), French woman of letters and salon hostess, by marriage Countess of Boufflers Marie Charlotte Schaefer (1874–1927), early Texas physician and the first woman to become a faculty member of the University of Texas Medical Branch Marie Charlotte de La Tour d'Auvergne (1729–1763), French noblewoman Marie Charlotte de La Trémoille (1632–1682), French noblewoman, by marriage Duchess of Saxe-Jena