L&I may refer to:
Government Pennsylvania Department of Labor and Industry Washington State Department of Labor and Industries
Transportation Lafayette & Indianapolis Railroad, a predecessor company of the Central Railroad of Indiana Louisville and Interurban Railroad, a defunct railroad in the US state of Kentucky
See also Maryland Department of Labor, previously the Maryland Department of Labor and Industry Minnesota Department of Labor and Industry (DLI) Oregon Bureau of Labor and Industries (BOLI) Virginia Department of Labor and Industry (DOLI) Ministry of Labour