Marie-Jo is a feminine compound given name which may refer to:
People Marie-Jo Bonnet (born 1949), French historian and lesbian feminist Marie-Josèphe Bonnet Marie-Jo Lafontaine (born 1950), Belgian sculptor and video artist Marie-Jo Pelletier (born 1997), Canadian former ice hockey player Marie-Jo Thério (born 1965), Canadian actress and musician Marie-Jo Thiel (born 1957), French theologian, medical doctor, and professor of ethics Marie-Jo Zarb, French lyricist, director and producer Marie-Jo Zimmermann (born 1951), French politician
Fictional characters Marie-Jo Cotin, a main character in A Very Secret Service, a French television series which aired from 2015 to 2018 the protagonist of Marie-Jo and Her Two Lovers, a 2002 French film