Lessore is a surname. Notable people with the surname include:
Ada Louise Powell née Lessore (1882–1956), English designer and calligrapher Émile Lessore (1805–1876), French ceramic artist and painter Helen Lessore (1907–1994), English gallerist Nathanael Lessore (born 1990), English author Thérèse Lessore (1884–1945), English artist