The 2000–01 Nebraska Cornhuskers men's basketball team represented the University of Nebraska–Lincoln during the 2000–01 NCAA Division I men's basketball season. Led by head coach Barry Collier, the Cornhuskers competed in the Big 12 Conference and played their home games at the Bob Devaney Sports Center.
On December 16, 2000, Nebraska defeated Miami 72–64 in the Orange Bowl Basketball Classic. Steffon Bradford led the Cornhuskers with 21 points and 9 rebounds.
Nebraska finished the season with a 14–16 record. The Cornhuskers season ended with a 62–58 loss to Kansas State in the Big 12 tournament on March 8, 2001.
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