NGC 5406 is a barred spiral galaxy in the constellation of Canes Venatici. Its velocity with respect to the cosmic microwave background is , which corresponds to a Hubble distance of . However, seven non-redshift measurements give a much closer mean distance of . It was discovered by German-British astronomer William Herschel on 16 May 1787.

NGC 5406 is a LINER galaxy, i.e. a galaxy whose nucleus has an emission spectrum characterized by broad lines of weakly ionized atoms.

According to Abraham Mahtessian, NGC 5406 and form a pair of galaxies.

Supernovae Two supernovae have been observed in NGC 5406: SN 1977B (type unknown, mag. 14) was discovered by Hungarian Astronomer Miklós Lovas on 18 March 1977. PSN J14002117+3854517 (TypeII, mag. 18.2) was discovered by Paolo Campaner and the Italian Supernovae Search Project (ISSP) on 18 February 2015.

See also List of NGC objects (5001–6000)

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