Fluorosulfonyl isocyanate is an organic chemical compound with the molecular formula .

Synthesis Fluorosulfonyl isocyanate can be made in a reaction of sulfonyl bisisocyanate and fluorosulfonic acid:

It is also formed in an exchange of halogens in chlorosulfonyl isocyanate using sodium monofluoride:

Physical properties The compound forms a colorless, volatile liquid.

It is soluble in aprotic organic solvents.

Uses The compound is a highly reactive, versatile chemical used in synthesizing polymers, agrochemicals, and advanced materials, notably acting as a linker in click chemistry for drug discovery.

See also Chlorosulfonyl isocyanate Fluorosulfonyl azide Trifluoromethanesulfonyl azide

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