The 2004–05 Xavier Musketeers men's basketball team represented Xavier University in the 2004–05 college basketball season. They were led by head coach Sean Miller. The Musketeers were members of the Atlantic 10 Conference and played their home games at the Cintas Center.
On November 27, 2004, Xavier defeated Miami (FL) 83–70 in the Orange Bowl Basketball Classic.
The Musketeers finished with a 17–12 record. They were eliminated from the A-10 tournament in the second round in a 73–68 loss to Saint Joseph's on March 11, 2005.
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