The 2025–26 Cal Poly Mustangs women's basketball team represents California Polytechnic State University, San Luis Obispo during the 2025–26 NCAA Division I women's basketball season. The Mustangs, led by fourth-year head coach Shanele Stires, play their home games at the Robert A. Mott Athletics Center in San Luis Obispo, California as a member of the Big West Conference.

Previous season The Mustangs finished the 2024–25 season 14–18, 8–12 in Big West play, to finish in eighth place. They upset UC Santa Barbara, before falling to eventual tournament champions UC San Diego in the quarterfinals of the Big West tournament.

Preseason On October 16, 2025, the Big West released their preseason poll. Cal Poly was picked to finish eighth in the conference.

Preseason rankings +Big West Preseason Poll Place Team Votes 1 91 (4) 2 90 (4) 3 83 (1) 4 77 (2) 5 61 6 57 7 51 8 Cal Poly 34 9 27 10 20 11 14

Source:

Preseason All-Big West Team No players were named to the Preseason All-Big West Team.

Roster

Schedule and results

!colspan=12 style=""| Exhibition

!colspan=12 style=""| Regular season

Sources:

References