Caine may refer to:

People Caine (surname), a name (including a list of people with the surname)

Fictional characters Caine, a character and the main antagonist from the animated series The Amazing Digital Circus Caine Soren, a character in the novel series Gone by Michael Grant Caine, an alternate spelling of the biblical Cain, and mythical first Vampire in the World of Darkness fictional universe Caine, the antihero of the Heroes Die novel written by Matthew Stover Caine the Longshot, a character in the manga and anime series Trigun Caine, one of Corwin's brothers in The Chronicles of Amber series of fantasy novels Horatio Caine, from the CSI: Miami television series Kwai Chang Caine, a Shaolin monk from the Kung Fu television series Caine "Kaydee" Lawson, the main character in Menace II Society film Solomon Caine, a character in the Driver video game franchise U.S.S. Caine, fictional ship of The Caine Mutiny franchise

Places La Caine, a commune in Basse-Normandie, France Río Caine, a river in Bolivia

Other uses Caine Prize, for African Writing CAINE Linux, a digital forensics Linux distribution Caine (film), an action thriller film in the John Wick franchise Caine, a person featured in the Holy Bible.

See also Cane (disambiguation) Cain (disambiguation) Kaine (surname) Kaine (disambiguation) Kain (disambiguation) Kane (disambiguation)