HQ-355, is an analogue of the sedative and hypnotic drug methaqualone developed in the late 1970s. It is a derivative of methaqualone substituted with a fluorine on the 2-methyl group. It has similar effects to methaqualone in animal studies but with slightly higher potency and an improved side effect profile. HQ-355 itself was never developed for medical uses, but its 6-amino derivative afloqualone did pass human trials and has seen some limited clinical application as a muscle relaxant.
See also List of methaqualone analogues
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