Mirembe is a surname. Notable people with the surname include:
Abigaba Cuthbert Mirembe (born 1975), Ugandan politician and engineer Drake P Mirembe (), Ugandan computer scientist Doreen Mirembe (born 1987), Ugandan actress, filmmaker, producer Enid Mirembe (), Ugandan beauty pageant contestant Lydia Daphine Mirembe (born 1985), Ugandan politician