The () was a diplomatic mission dispatched by the Senate of Macau to Nagasaki in July 1640. Its purpose was to try and reverse the Tokugawa shogunate's decision to end nearly a century of Portuguese trade in Japan in 1639.

The ban followed the Shimabara Rebellion, which the shogunate incorrectly blamed the Portuguese for aiding through the smuggling of supplies and missionaries. Since Macau's economy relied on the annual trade with Japan, the city's assembly resolved on March 13, 1640, to dispatch four ambassadors, Luís Pais Pacheco, Rodrigo Sanches de Paredes, Gonçalo Monteiro de Carvalho and Simão Vaz de Paiva, along with sailors and slaves, totaling 74 crew. All participants knew that the risk of death was almost certain.

The embassy's vessel arrived at Nagasaki on July 6, 1640, however, all of the delegation members were imprisoned and detained on Dejima by Kagazume Minbu and Nonoyama Shinbei while their appeals were sent to Edo. On 3–4 August 1640, 61 members of the mission, including all four ambassadors, were beheaded on Martyrs' Mount in Nagasaki, and their ship was burned in the harbor. 13 men were spared and sent back to Macau on 1 September to deliver the message of the embassy's fate.

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