CBS 15 may refer to one of the following television stations in the United States:
Currently affiliates WANE-TV in Fort Wayne, Indiana WKOF in Syracuse, New York
Formerly affiliated KCLO-TV in Rapid City, South Dakota (1988–2026) WLYH-TV (now WXBU) in Lancaster, Pennsylvania (1963–1995) WXVT (now WFXW) in Greenville, Mississippi (1980–2016)