Gambrill is a surname. Notable people with the surname include:
Anne Gambrill (1934–2026), New Zealand lawyer and judge Charles D. Gambrill (1834–1880), American architect Mike Gambrill (1935–2011), British track cyclist Stephen Warfield Gambrill (1873–1938), American politician
See also Gambrill House, historic house in Maryland, U.S. Gambrills, Maryland Gambrell, another surname Gambill (surname), another surname