NGC 2599 is a large spiral galaxy in the constellation of Cancer. Its velocity with respect to the cosmic microwave background is , which corresponds to a Hubble distance of . It was discovered by German-British astronomer William Herschel on 16 November 1784.

NGC 2599 is a LINER galaxy, i.e. a galaxy whose nucleus has an emission spectrum characterized by broad lines of weakly ionized atoms.

NGC 2599 is a galaxy whose nucleus shines brightly in the ultraviolet and is listed in the Markarian catalogue as Mrk 389.

Supernova One supernova has been observed in NGC 2599: SN 1965P (type unknown, mag. 15.7) was discovered by Howard S. Gates on 6 March 1965.

See also List of NGC objects (2001–3000)

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