Mesnil is a surname, and may refer to:
Félix Mesnil (1868–1938), French zoologist, biologist, botanist, mycologist and algologist François-Jean de Mesnil-Durand (1736–1799), French tactician Jacques Mesnil (1872–1940), Belgian journalist, art critic, art historian and anarchist Romain Mesnil (born 1977), French pole vaulter
See also de Ménil