Salustiano is a surname and a given name. Notable people with the name include:
Given name: Salustiano de Olózaga y Almandoz (1805–1873), Spanish politician, diplomat, Prime Minister of Spain Salustiano Jerônimo dos Reis, Baron of Camaquã, Brazilian Marshal Salustiano Candia (born 1983), Paraguayan footballer Salustiano Contreras, Cuban baseball infielder Salustiano Santos (1918–1995), Spanish footballer Salustiano Paco Varela (1914–1987), Argentine tango bandoneonist, bandleader and composer
Surname: Matheus Salustiano (born 1993), Brazilian footballer