David Henderson may refer to:
Academy David Henderson (philosopher) (born 1954), American philosopher David Henderson (psychiatrist) (1884–1965), Scottish psychiatrist David W. Henderson (1939–2018), American professor of mathematics David Willis Wilson Henderson (1903–1968), Scottish microbiologist, director of MRE, Porton Down
Economics David Henderson (economist) (1927–2018), chief economist at the OECD in Paris from 1984 to 1992 David R. Henderson (born 1950), American economist
Journalism David Henderson (broadcaster) (born 1970), Scottish journalist/newsreader working for BBC Scotland David Henderson (American journalist), CBS Network News television and radio journalist
Politics David B. Henderson (1840–1906), U.S. politician of the 1890s and 1900s David Henderson (Canadian politician) (1841–1922), Canadian member of parliament David N. Henderson (1921–2004), U.S. representative from North Carolina
Sports David Henderson (footballer) (1868–1933), Scottish football player (Liverpool FC) Dave Henderson (1958–2015), Major League Baseball player Dave Henderson (footballer) (born 1960), retired Irish football goalkeeper David Henderson (basketball) (born 1964), former Duke co-captain and head basketball coach at University of Delaware David C. Henderson (born c. 1917), American football player and coach of football and basketball Dave Henderson (ice hockey) (born 1952), Canadian-born French ice hockey coach and player
Others David Henderson (British Army officer) (1862–1921), senior British Army and, later, RAF officer David Ezekiel Henderson (1879–1968), U.S. federal judge David Henderson (poet) (1942–2026), poet associated with the Umbra workshop and Black Arts Movement Davy Henderson (born c. 1962), Scottish musician, The Fire Engines, Win, The Nectarine No. 9 David Henderson (property developer), property developer in New Zealand David Henderson, English pilot and businessman prosecuted for his role in the 2019 English Channel Piper PA-46 crash