Eguiguren is a surname. Notable people with the surname include:
Francisco Eguiguren Correa (born 1967), Chilean Business Administrator and politician Jesús Eguiguren (born 1954), Spanish academic, jurist, President of the Basque Parliament José Javier Eguiguren (1816–1884), acting President of Ecuador José Manuel Eguiguren Urrejola (1811–1883), Chilean politician and lawyer Julián Carlos Andiano Eguiguren (born 1951), Spanish racing cyclist Luis A. Eguiguren (1887–1967), Peruvian educator, magistrate, historian and politician Macarena Campomanes Eguiguren (born 1964), Spanish amateur golfer Manuel Eguiguren Galarraga (1930–2012), the Roman Catholic titular bishop of Salapia, Bolivia Martín Eguiguren (born 1941), Argentine weightlifter Maximiano Errázuriz Eguiguren (born 1945), Chilean conservative politician