The 2010 Southern Utah Thunderbirds football team represented Southern Utah University as a member of the Great West Conference (GWC) during the 2010 NCAA Division I FCS football season. Led by third-year head coach Ed Lamb, the Thunderbirds compiled an overall record of 6–5 with a mark of 4–0 in conference play, winning the GWC title. The team played home games at Eccles Coliseum in Cedar City, Utah.
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