Alcalde is a Spanish surname related to alcalde, the Spanish title for a mayor. Notable people with the name include:

Antonio Alcalde Barriga (1701–1792), Spanish Catholic prelate and bishop Cristina Alcalde (born 1980), Spanish cyclist Gustavo Alcalde (born 1955), Spanish politician Jorge Alcalde (1911–2005), Peruvian footballer Jorge Alcalde Lagranja (born 1968), Spanish journalist, science advocate and writer Luisa María Alcalde Luján (born 1987), Mexican politician Manuel Alcalde (1956–2004), Spanish race walker Mario Alcalde (1926–1971), American actor M. Cristina Alcalde, Peruvian anthropologist and academic Moisés Alcalde Virgen (born 1971), Mexican politician Núria Aliaga-Alcalde, Spanish chemist and academic Pedro Alcalde (born 1959), Spanish musician, composer and conductor Tati Alcalde (born 1964), Spanish footballer Teodoro Alcalde (1913–1995), Peruvian footballer Zenaida Alcalde (born 1981), Spanish circus performer, actress and teacher