1-Dimethylaminomethyl-LSD is a lysergamide derivative related to the psychedelic drug lysergic acid diethylamide (LSD). https://erowid.org/library/books_online/tihkal/tihkal26.shtml "1-Hydroxymethyl-LSD, 1-dimethylaminomethyl-LSD and 2-iodo-LSD. These three additional compounds are shown here because they were described in a synthetic flurry that followed the discovery the activity of LSD. But at the moment I know neither their internal Sandoz codes nor if they had ever been explored in man. This is a kind of frustrating catch-all entry, in that the long index will send you here, and once here you realize that nothing is known. Well, at least the compounds are known, and perhaps there is something in the Sandoz vaults that might be interesting. I do not have access to them." It was synthesized and described by Albert Hofmann and Franz Troxler at Sandoz in 1957. According to Alexander Shulgin in his 1997 book TiHKAL (Tryptamines I Have Known and Loved), 1-dimethylaminomethyl-LSD has been limitedly described, and it is unknown whether it was ever tested in humans. The 2-dimethylaminomethyl-LSD positional isomer has also been described, and was found to have 18.5% of the antiserotonergic activity of LSD in vitro.
See also Substituted lysergamide OML-632 (1-hydroxymethyl-LSD) MLD-41 (1-methyl-LSD) ALD-52 (1-acetyl-LSD)
References
External links 1-Dimethylaminomethyl-LSD - Isomer Design LSD-25 (Discusses 1-Dimethylaminomethyl-LSD) - TiHKAL - Erowid LSD-25 (Discusses 1-Dimethylaminomethyl-LSD) - TiHKAL - Isomer Design