Berzsenyi is a surname. Notable people with the surname include:
Barnabás Berzsenyi (1918–1993), Hungarian fencer Dániel Berzsenyi (1776–1836), Hungarian poet George Berzsenyi (born 1938), Hungarian-American mathematician Mária Berzsenyi (born 1946), Hungarian handball goalkeeper Ralph Berzsenyi (1909–1978), Hungarian sport shooter