Axente is a surname. Notable people with the surname include:
Cătălina Axente (born 1995), Romanian wrestler Ioan Axente Sever (1821–1906), Romanian revolutionary in Austria-Hungary Mircea Ionuț Axente (born 1987), Romania football player Mircea Axente (footballer, born 1944), Romanian football player and referee Vanessa Axente (born 1995), Hungarian model