Mohamed Zerguini (, 30 January 1922 – 21 June 2001) was an Algerian politician. He served as president of the Algerian Olympic Committee from 1968 to 1983, and in 1974 he became a member of the International Olympic Committee. He was also the Minister of Post and Telecommunications from 23 April 1977 to 15 July 1980, in the Boumédiène IV and Abdelghani I governments.
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