Enzio () may refer to
Enzio, legitimate son of Manfred of Sicily by his wife Helena; he was confined to prison his entire life Enzio Boldewijn (born 1992), Dutch footballer Enzio d'Antonio (1925–2019), Italian Roman Catholic bishop and archbishop Enzio von Pfeil (born 1953), German economist Enzio Reuter (1867–1951), Finnish entomologist