Maria Isabella may refer to:

María Isabella of Spain (1789–1848), Queen of the Two Sicilies Princess Maria Isabella of Naples and Sicily (1793–1801), daughter of Ferdinand I of the Two Sicilies and Maria Carolina of Austria Archduchess Maria Isabella of Austria (1834–1901), daughter of Leopold II, Grand Duke of Tuscany and Princess Maria Antonia of the Two Sicilies Duchess Maria Isabella of Württemberg (1871–1904)

See also My Life for Maria Isabella, 1935 German film