Yoqubov or Yokubov is an Uzbek-language variant of the surname Yakubov. Notable people with the surname include:

Doston Yokubov (born 1995), Uzbek Olympic weightlifter Odil Yoqubov (1926–2009), Uzbek writer Oʻrinbek Yoqubov (1917–1989), Soviet Uzbek officer, Hero of the Soviet Union See also

Ikram Yakubov, Uzbek intelligence officer