George Wolfe may refer to:
George C. Wolfe (born 1954), African-American playwright and director George Wolfe (Irish politician) (1860–1941), Irish Cumann na nGaedhael TD 1923–1932 George Wolfe (CPA), US government administrator in Iraq George Wolfe (cartoonist) (1911–1993), American cartoonist George Wolfe (footballer) (1878–1958), English footballer
See also George Wolf (1777–1840), governor of the U.S. state of Pennsylvania George Wolff (disambiguation)