Clarence is a surname. Notable people with the surname include:

Juma Clarence (born 1989), Trinidadian footballer Lovell Burchett Clarence (1838–1917), British barrister and Puisne Justice of the Supreme Court of Ceylon O. B. Clarence (1870–1955), English film and stage actor William Henry Clarence (1856–1879), king or hereditary chief of the Miskito people

See also FitzClarence, surname of an illegitimate branch of the House of Hanover, the descendants of Prince William, later King William IV of the United Kingdom, and his mistress Dorothea Jordan