Hyperaspis unimaculosa is a species of beetle of the family Coccinellidae. It is found in Brazil.

Description Adults reach a length of about 2.6–3.0 mm. They have a black body and yellow head. The pronotum is black, with the anterior one-sixth and lateral one-fourth yellow. The elytron is black with the lateral and apical margins yellow.

Etymology The species name is derived from Latin uno (meaning one) and macula (meaning spot) and refers to the similar species Hyperaspis uninotata.

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