Comber is a surname, and may refer to:
Bobbie Comber (1886–1942), British comedian, singer and actor Casey Comber (born 1996), American middle-distance runner Charles Comber (1891–1966), Australian rules footballer George Comber (1856–1929), English undertaker and cricketer Harold Frederick Comber (1897–1969), English horticulturist and plant collector Jack Comber (1919–1992), Australian politician James Boughtwood Comber (1929–2005), Scottish plantation manager and botanist John Comber (1861–1903), English cricketer John William Comber (1906–1998), American Catholic missionary Joseph Comber (1911–1976), English cricketer Karen Le Comber (born 1969), New Zealand cricketer Ken Comber (1939–1998), New Zealand politician and accountant Leon Comber (1921–2023), British military and police officer and book publisher, in British India Lillian Comber, pen name Lillian Beckwith (1916–2004), English writer Michael Comber (born 1989), English cricketer Mick Comber (1903–1975), Australian rules footballer Robert Comber (c.1816–1858), English cricketer Thomas Comber (dean of Carlisle) (1575–1653), English cleric and linguist Thomas Comber (dean of Durham) (1645–1699), English churchman Thomas J. Comber (1852–1887), English Baptist missionary in the Congo region Tony Comber (1927–2022), Archdeacon of Leeds