Gnaeus Aufidius may refer to:
Gnaeus Aufidius (historian), politician, historian, and perhaps a jurist of the late 2nd and early 1st century BCE Gnaeus Aufidius (tribune 170 BC), nobleman of ancient Rome, who lived in the 2nd century BC
See also Gnaeus Aufidius Orestes (died 1st century BC), Roman politician elected consul in 71 BC