2-Methoxyphenethylamine (2-MPEA) is a drug of the phenethylamine family. It is one of the methoxyphenethylamine positional isomers.
Use and effects The effects of 2-MPEA in humans have not been reported and are unknown.
Pharmacology
The drug showed very low affinity for the serotonin receptors in the rat stomach fundus strip (A2 = 3,020nM). In another study, it showed no affinity for the serotonin 5-HT2A or 5-HT2C receptors (Ki = >10,000nM). 2-MPEA is a potent full agonist of the human trace amine-associated receptor 1 (TAAR1) ( = 144nM; = 95%).
History
2-MPEA was first described in the scientific literature by at least 1943. It was included as an entry in Alexander Shulgin's 2011 book The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds.
See also Substituted methoxyphenethylamine Methoxyphenethylamine 2-Methoxyamphetamine Methoxyphenamine
References
External links 2-MPEA