Schaffhausen is a town in Switzerland. Schaffhausen could also refer to:

Canton of Schaffhausen, a canton of Switzerland, centered at the eponymous town Schaffhausen District, a district within the canton Schaffhausen railway station, a train station within the town Schaffhauser Kantonalbank, a bank of the canton Aaron Schaffhausen (fl. 2012), American murderer Joanna Schaffhausen, American novelist

See also Nicolaus Schafhausen Hermann Schaaffhausen Schaffhauseria Schafhausen i.E. railway station