Sipho is a South African given name. Notable people with the surname include:
Sipho Binda (1952–2006), South African military commander Sipho Burns-Ncamashe (1920–1996), South African poet, short story writer, and Xhosa imbongi (praise poet) Sipho Chaine (born 1996), South African soccer player Sipho Dlamini, Swazi Olympic middle-distance runner Sipho Gcabashe, South African politician and businessman Sipho Gumede (1952–2004), South African jazz musician and composer Sipho Hlomuka (born 1980), South African politician Sipho Jele, member of the banned Swazi political party Sipho Mabona, Swiss origami master Sipho Mabuse (born 1951), South African singer-songwriter Sipho Mashele (born 1987), South African cricketer Sipho Mbatha, South African politician Sipho Mbule (born 1998), South African professional soccer player Sipho Mchunu (born 1951), South African musician Sipho Mfundisi (born 1948), South African politician Sipho Mngomezulu (born 1982), South African footballer Sipho Moyo, Zimbabwean economist Sipho Mumbi (born 1983), Zambian retired footballer Sipo Mzimela (1935–2013), South African politician, anti-apartheid activist, and Christian minister Sipho Ndlovu (born 1994), Zimbabwean footballer Sipho Ngema (1972–2020), South African actor Sipho Ngwenya, the first democratically elected mayor of the Greater City of Durban Sipho Nkosi, South African politician Sipho Philip Mutsi (1967–1985), regional organiser for the Congress of South African Students (COSAS) Sipho Sepamla (1932–2007), South African contemporary poet and novelist Sipho Sibiya (born 1971), South African retired soccer player Sipho Siboza (born 1964), South African politician Sipho Thwala, South African rapist and serial killer Sipho William Lubisi, South African politician
Middle name Baldwin Sipho Ngubane (1941–2021), South African politician Cleopas Sipho Dlamini (born 1952), Liswati business executive Clint Sipho Sephadi (born 1973), South African retired professional footballer Zakhele Sipho Mkhize (born 1950), South African politician