Cyclopropylamine is the organic compound with the formula . It is a simple amine derivative of cyclopropane. As a precursor to pesticides and pharmaceuticals, it is produced on a multi-ton scale from the carboxamide. Cyclopropylamine is first member of the aminocycloalkanes, which includes cyclobutylamine, cyclopentylamine, and cyclohexylamine.
Cyclopropylamines Many aminocyclopropanes are known, most prominently the amino acid aminocyclopropane-1-carboxylic acid.
The cyclopropylamine group is featured in several pharmaceutical drugs: Simeprevir, used to treat hepatitis C infections Risdiplam, used to treat spinal muscular atrophy ciprofloxacin, an antibiotic.
Cyclopropylamines can be prepared by the Kulinkovich reaction, by dialkylation of bromonitromethane, and various cyclopropanations.
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