May 16 May Gaza health officials said that over 100 people including women and children were killed in Israeli attacks in Gaza. The IDF said that it conducted airstrikes on more than 150 militant targets including anti-tank missile launch posts, cells and buildings used to conduct attacks on its forces. It also said that it killed several militants who were at an observation post during ground operations in north Gaza, destroyed several tunnel shafts and other infrastructure and killed several militants during ground operations in Rafah and killed militants attempting to plant a bomb in the Morag Corridor. The IDF said that it conducted attacks on Hudaydah Port and Port of Salif in response to Houthi attacks on Israel, and destroyed infrastructure at ports controlled by Houthis and used for weapons transfers. The Houthi-controlled Health Ministry stated that one person was killed and nine others were wounded in the airstrikes. Israeli forces issued evacuation orders for residents of Gaza to move south. UN's Interim Forces in Lebanon (UNIFIL) said that a “large group of individuals” confronted UN troops in South Lebanon during a routine patrol and called the Lebanese government to ensure there are no obstructions to the peacekeeping force. An Israeli police officer was injured in a stabbing attack in the Old City of Jerusalem. The attacker was shot dead by Israeli police.
17 May The Gaza Health Ministry reported that at least 153 people were killed in Israeli attacks throughout Gaza in the past 24 hours, increasing its count of the Palestinian death toll in Gaza to 53,272. Israeli forces announced that they started a major offensive in Gaza. The IDF said that it downed a drone apparently launched by the Houthis. Al Jazeera reported that an Israeli strike hit a vehicle carrying people evacuating from eastern Khan Yunis, killing an elderly man and his two grandchildren. One person was killed in an Israeli drone strike on a car in Tyre District. The IDF said that it killed a Hezbollah commander who was involved in restoring Hezbollah's capabilities in the Beaufort Castle area. Gaza rescuers said that an Israeli strike hit a tent west of Khan Yunis, killing one person and injuring five others including a girl, a young woman and a pregnant woman. Al Jazeera reported that an Israeli strike hit a house in Jabalia, killing four children. The IDF said that it destroyed a "strategic" Hamas tunnel measuring 2 km while operating in north Gaza. Al Jazeera reported that IDF fire hit an elderly Palestinian man in the vicinity of the entrance to Jenin refugee camp, injuring him. Al Jazeera reported that an Israeli strike hit Deir el-Balah, killing nine family members including three children.
18 May The Gaza Health Ministry reported that at least 67 people were killed in Israeli attacks throughout Gaza in the past 24 hours, increasing its count of the Palestinian death toll in Gaza to 53,339. The IDF said that it downed a ballistic missile fired towards Israel by the Houthis. Israeli media outlet Channel 12 reported, citing the IDF that a second unsuccessful missile launch was attempted from Yemen. The Houthis said that they launched a hypersonic Palestine 2 missile and a Zulfiqar missile towards Ben Gurion Airport. The Gaza Health Ministry reported that least 151 Palestinians, including children were killed in Israeli strikes in Gaza. Al Jazeera reported that at least five more Palestinian journalists were included among those killed in Israeli strikes in recent days. Gaza media outlets reported that a lecturer who was the brother of former Hamas leader Yahya Sinwar and de facto leader of Hamas in the Gaza Strip Muhammad Sinwar was seriously wounded in an airstrike which hit a tent in Nuseirat along with his three children. NNA reported that an Israeli drone hit a car in the vicinity of a Lebanese army checkpoint in Beit Yahoun, injuring two people including a Lebanese soldier. The Gaza Health Ministry reported that all public hospitals in north Gaza went out of service. The IDF announced that it started a "broad" ground offensive in Gaza. It said that the IAF launched strikes on 670 Hamas targets in the last week including weapons depots, militant cells, tunnels and anti-tank launch sites, killed dozens of militants, destroyed militant infrastructure, and holding "strategic" areas in Gaza, using five divisions. The IDF said that it downed one rocket fired from central Gaza towards Kissufim, while another rocket hit an open area. al-Qassam Brigades said that it launched the rockets. It later warned residents to evacuate from Al-Qarara suburb of Khan Yunis and southern Deir al-Balah. Israeli Prime Minister Benjamin Netanyahu announced that "basic amount" of food will be allowed into Gaza after blocking aid for more than two months. An Israeli strike hit a tent on Al-Barakah Street in Deir al-Balah, killing a Palestinian woman.
19 May The Gaza Health Ministry reported that at least 136 people were killed in Israeli attacks throughout Gaza in the past 24 hours, increasing its count of the Palestinian death toll in Gaza to 53,486. At least 126 Palestinians including civilians were killed in Israeli strikes on Gaza. Wafa reported that a Palestinian boy was severely beaten and detained by Israeli forces in Beit Ummar. A commander of the Al-Nasser Salah al-Deen Brigades was killed in a clash with Israeli special forces in Khan Yunis. Israeli forces also detained his wife and child. The IDF said that Israeli warplanes struck more than 160 targets in Gaza in the last day including militant cells, anti-tank missile launch sites, tunnels, a weapons depot, buildings used by militant groups, booby-trapped structures and a command center. The IDF issed evacuation orders for Palestinians in Khan Yunis, Bani Suheila and Abasan al-Kabira to move to al-Mawasi before it launches an "unprecedented attack". It also declared the entirety of Khan Yunis as a combat zone. The IDF said that it destroyed a tunnel used by Hamas for an attack which killed two soldiers on 3 May in Rafah. An Israeli strike hit a school sheltering displaced people in Nuseirat, killing at least seven Palestinians, including a woman and a young girl and wounded 18 others including children. The IDF said that it targeted Hamas militants in a command center in the school. The al-Qassam Brigades claimed that several Israeli troops were killed and injured in an ambush in Atatra, Beit Lahia. A 16-year-old Palestinian was detained after clashes between residents and Israeli forces in Sa'ir. Three UNRWA employees were killed in Gaza. One person was killed in an Israeli drone attack in Houla. The IDF said that it killed a Redwan force militant. Three people were injured in two other incidents in the vicinity of the Lebanese border. The IDF announced that a soldier from 601st Combat Engineering Battalion was killed while fighting in north Gaza, increasing the IDF death toll in Gaza to 416. An IDF investigation found that he was killed after being hit by friendly fire. Houthis announced a "maritime blockade" against the Port of Haifa. An alleged Hamas militant was arrested in Denmark for purchasing drones to be used in militant attacks.
20 May The Gaza Health Ministry reported that at least 87 people were killed in Israeli attacks throughout Gaza in the past 24 hours, increasing its count of the Palestinian death toll in Gaza to 53,573. Al Jazeera reported that an Israeli strike hit a home in Deir el-Balah, killing 12 people and several others went missing. Al Jazeera reported that an Israeli strike hit a petrol station in Nuseirat refugee camp, killing 15 people including children. The Gaza Health Ministry said that an Israeli strikes hit a house and a school serving as shelter in north Gaza, killing at least 22 people including children and women. The IDF said it struck a command center and warned civilians in advance. Al Jazeera reported that Israeli strikes in Khan Yunis refugee camp killed five people including three children. Al Jazeera reported that ten people including a 17-year-old boy were detained by Israeli forces during an operation in the West Bank. NNA reported that an Israeli drone strike on a motorcycle in the vicinity of Majdal Zoun killed one person and injured five others. The IDF said that it struck more than 100 militant targets including a tunnel, a weapons depot, militants, buildings used by militant groups including a building used by PIJ for storing weapons and observation posts. The IDF and Shin Bet also said that they killed the commander of Hamas's aerial forces in north Gaza in a strike three days prior. Wafa reported that dozens of people including journalists suffered suffocation during an Israeli operation in Askar al-Qadeem refugee camp, east of Nablus. NNA reported that firing from an Israeli drone hit fishermen in Ras an-Naqoura. A Palestinian paracyclist was among those killed in an Israeli strike on south Gaza. The Hungarian Parliament passed a bill for exiting the International Criminal Court in response to its issuance of arrest warrants against Israeli Prime Minister Benjamin Netanyahu and former Defense Minister Yoav Gallant for alleged war crimes in Gaza. The IDF said that it killed the commander of Hezbollah forces in Al-Mansouri in a drone strike. Al Jazeera reported that at least 326 deaths in Gaza were caused by malnutrition and lack of medicine since Israel's complete blockade started on 2 March.
21 May The Gaza Health Ministry reported that at least 82 people were killed in Israeli attacks throughout Gaza in the past 24 hours, increasing its count of the Palestinian death toll in Gaza to 53,655. Hospital officials said that fourteen members from one family including eight children were included among those killed in an Israeli strikes in Khan Yunis. AP reported that a one-week-old infant was included among those killed in an Israeli strike in central Gaza. The IDF announced that a soldier from the 51st Company in the 82nd Battalion of the 7th Brigade was killed while another was injured during combat in south Gaza following the collapse of a building where their unit was operating, setting off an explosion, increasing the IDF death toll in Gaza to 417. The UK announced sanctions on far-right Israeli settler Daniella Weiss, whom they called the "godmother" of Israeli settler movements. Lebanese media reported that an Israeli drone hit a vehicle in Ain Baal. The IDF said that it killed “an experienced engineer” in Hezbollah's weapons research and development division. Twenty Palestinians including three women were detained by Israeli forces from the West Bank. Israeli forces fired at a diplomatic delegation from foreign nations visiting Jenin refugee camp. The IDF said that it fired warning shots after they deviated from an agreed route. It later apologized. NNA reported that an Israeli drone hit Yatar, killing one person. The IDF said that it killed a commander of Hezbollah's Radwan force. The IDF said that the IAF struck more than 115 targets in Gaza in the last day including a drone strike in north Gaza which killed a Nukhba Force militant in its East Jabalia Battalion who participated in the 7 October attacks, rocket launchers, buildings used by militant groups, tunnels, other infrastructure, and militant cells. It added that the Israeli Navy also conducted shelling in north Gaza to assist ground forces operating in the area. The IDF said that it detained a Palestinian suspected of directing the 2025 al-Funduq shooting from western Jenin. The IDF said that air defences downed a rocket fired from north Gaza towards Ashkelon. The PIJ claimed responsibility. The IDF later issued evacuation orders for residents of more than a dozen areas of north Gaza to move south. NNA reported that an Israeli strike hit Aitaroun, killing one person. It also reported that several others were injured. The IDF said that it killed a Hezbollah militant.