Genesio and Genésio are, respectively, the Italian and Portuguese forms of Genesius, a male given name pertaining to several saints and historical personalities. It also occurs as a surname. Notable people with the name include: Antonio Genesio Maria Panizzi (1797–1879), known as Anthony Panizzi, British-Italian patriot Bruno Génésio (born 1966), French football manager and former player Genésio Goulart (1954–2021), Brazilian politician Leanderson da Silva Genésio (born 1997), known as Lelê, Brazilian footballer

See also Jenesio San Genesio (disambiguation)