Roseborough is a surname. Notable people with the surname include:
Barry Roseborough (1932–1992), Canadian football player Cliff Roseborough (c. 1910–1984), Canadian football player Teresa Wynn Roseborough (born 1958), American lawyer and former Deputy Assistant Attorney General Viola Roseborough, stage name of Viola Roseboro' (1857—1945), American literary editor and briefly an actress
See also Rosebraugh, another surname