Cencio () is an Italian male given name, most common in the Middle Ages, originating as an apheretic form of Vincenzo or Innocenzo. Notable people with the name include:

Cencio I Frangipane (), Italian nobleman Cencio II Frangipane (), Italian nobleman Cencio Mantovani (1941–1989), Italian cyclist Cencio Massola (1885–1944), Italian sports sailor Cencio Savelli (–1227), head of the Catholic Church and ruler of the Papal States as Pope Honorius III

See also Cencio la Parolaccia, a restaurant in Trastevere, Rome Cenci Cenzo

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