Milgrim is a surname derived from the Yiddish word for pomegranate (מילגרוים, Milgroim). Notable people with the surname include:

Lynn Milgrim (born 1944), American actress Roger M. Milgrim, American intellectual property lawyer Sally Milgrim (1898–1994), American businesswoman and fashion designer Sarah Milgrim, Jewish-American victim of a 2025 shooting

See also Milgram, similar surname Milgrom, similar surname