Anhalonine, also known as 1-methyl-6-methoxy-7,8-methylenedioxy-1,2,3,4-tetrahydroisoquinoline, is a tetrahydroisoquinoline alkaloid found in Lophophora williamsii (peyote) and many other cactus species. Peyote contains 3% anhalonine. The drug is known to be pharmacologically active and is said to be similar in its activity to anhalonidine. Arthur Heffter tried anhalonine via self-experimentation at an oral dose of 100mg and found that it was inactive aside from mild sleepiness. Similarly, Prentiss and Morgan (P&M) tried pure anhalonine at doses of up to 200mg without any effects. Anhalonine was isolated from peyote by Louis Lewin in 1888 and was bioassayed by Heffter with his report published in 1898. P&M's report was published in 1896.
See also Substituted tetrahydroisoquinoline Lophophorine Peyophorine Lophophine
References
External links Anhalonine - Isomer Design Anhalonine - Trout's Notes