Isaac was one of the patriarchs of the Abrahamic faiths.

Isaac may also refer to:

Isaac (name), including a list of people and fictional characters with the given name or surname of Isaac and its variants

Organizations International Society for Analysis, its Applications and Computation International Society for Augmentative and Alternative Communication International Symposium on Algorithms and Computation

Places Great Isaac Cay, Bahamas Issac, Dordogne, Nouvelle-Aquitaine, France Isaac River, Australia Isaac Region, Australia Isaac's Harbour, Nova Scotia, Canada Isaac's Harbour North, Nova Scotia, Canada Port Isaac, Cornwall, United Kingdom

Other uses Infrared Spectrometer And Array Camera (ISAAC)), an instrument on the Very Large Telescope ISAAC (cipher), a cryptographically secure pseudorandom number generator ISAAC (comics), a supercomputer in Marvel Comics Isaac (talk show), a talk show hosted by Isaac Mizrahi List of storms named Isaac, used for various tropical cyclones "Isaac" (song), a song by Hollyn "Isaac", a song by Madonna, from her album Confessions on a Dance Floor Isaac, the northeasternmost country in the Fire Emblem universe continent Jugdral

See also Isaacs (disambiguation) Isaaq, a Somali clan Ishak (disambiguation) International Symposium on Symbolic and Algebraic Computation (ISSAC) Izak (disambiguation) Izzy (disambiguation) Zack (disambiguation)