The sack of Apamea was a sack in 573 during the Byzantine–Sasanian War of 572–591
history when Khosrow I was besieging Dara he sent Adarmahan at the head of an army with 6,000 soldiers to invade the Roman province of Syria.he burned around the city of Antioch and entered the city of Apamea. Adarmahan thoroughly sacked and burned Apamea, and captured 292,000 civilian.The Cambridge Companion to the Age of Justinian two thousand virgins whom Chos-roes was to send to the king of the Turks, chose self-immolation rather than submit to the humiliation of becoming the harem of the Turkish chagan in central Asia. the figure seems inflated, because the Persians could not have managed or fed so many prisonersThe Cambridge Companion to the Age of Justinian and despite the demographic disaster Apamea did survive as a smaller city Apamea's great Cathedral of the East, probably containing a relic of the True Cross, was never restored. Whether this was through lack of will or resources is unclearRoman Syria and the Near East p 423
References
Sources
Maas Michael, The Cambridge Companion to the Age of Justinian Butcher, Kevin. Roman Syria and the Near East