Adamopoulos or Adamopoulou is a Greek surname. Notable people with the surname include:
Ariadni Adamopoulou (born 2000), Greek athlete Giorgos Adamopoulos (1946–2023), Greek politician Nicholas Adamopoulos (born 1984), birth name of Nick Adams, Australian-born American political commentator and author Tasso Adamopoulos (1944–2021), French violist