Anomaloglossus megacephalus is a species of frog in the family Aromobatidae. It is endemic to Guyana.

Description The adult female frog can reach 28.3 mm in snout-vent length.

Habitat This diurnal frog has been found near streams in low-canopy forests high on tepui flatlands. Scientists observed it between 1060 and 1490 meters above sea level.

Reproduction Scientists have not observed oviposition. After the eggs hatch, the adult frogs carry the tadpoles to streams.

Threats The IUCN classifies this frog as data deficient. Its habitat is largely pristine and rarely visited by humans, but there is some gold mining in one area.

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